TCD provides noninvasive monitoring in diverse clinical situations, offering real-time physiological data without increasing patient risks or costs. ...
Stroke is one of the most serious complications that occur in children suffering from sickle cell disease (SCD)....
TCD has its importance in diagnosis, treatment decisionmaking, and prognosis of Sickle Cell Disease. By TCD measurement of elevated blood flow velocities (BFV), children, who may benefit from blood transfusions, can be identified even months before stroke. TCD guided, intensified therapy reduces stroke risk....
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