TCD provides real-time information about the blood flow in addition to the hemodynamic changes as a result of various physiological as well as pathological states. TCD can predict stroke by determination of high blood flow velocities, which allows indirect conclusions on stenosis or occlusion....
TCD has its importance in diagnosis, treatment decisionmaking, and prognosis of Sickle Cell Disease. By TCD measurement of elevated blood flow velocities (BFV), children, who may benefit from blood transfusions, can be identified even months before stroke. TCD guided, intensified therapy reduces stroke risk....
Patent Foramen Ovale (PFO) causing Right to Left Shunt (RLS) can be detected by TCD PFO-Test. RLS are direct connections between right (pulmonary) and left (systemic) circulation. By this connection blood can cross to the other circulation without passing pulmonary capillaries....
SARS-CoV-2 infection can be particularly dangerous in patients whose vascular function is already impaired by pre-existing conditions. This explains the typical clinical picture by causing circulatory disorders in the heart, as well as pulmonary embolism and vascular occlusions....