The SPIN and SPRING trials established the first evidence-based stroke prevention strategy for children with sickle cell anemia in Africa, combining TCD screening, fixed-dose hydroxyurea, and a state-supported clinical infrastructure....
Large vessel occlusions are a major challenge in stroke triage, where time is critical. A study in Frontiers in Neurology tested quantitative TCD metrics and found that waveform morphology — expressed through the Velocity Curvature Index — significantly improves detection accuracy. Combined with asymmetry measures,...
In a pilot study on patients recovering from aneurysmal subarachnoid hemorrhage, transcranial Doppler monitoring showed a significant reduction in middle cerebral artery flow velocity during exposure to Mozart’s classical music. The effect, absent in a silent control condition, suggests potential for music as a non-invasive...
A 2025 editorial in The Journal of Physiology raises a key issue in neurocritical care: the lack of a continuous, direct cerebral blood flow monitor. While several technologies are under development, transcranial Doppler offers a practical and established option for real-time cerebral flow assessment at...
Once considered optional, Transcranial Doppler (TCD) has become a key diagnostic tool in evaluating right-to-left shunts in cryptogenic stroke. This article summarizes how major neurological and cardiovascular guidelines describe its value, performance, and integration into diagnostic pathways....